Publications

• Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease, Kerr et al. (2017)
• Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures, CL Croft et al. (2017)
• Roles of tau protein in health and disease, T Guo et al. (2017)
• α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production, S Paillusson et al. (2017)
• The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy, P Gomez-Suaga et al. (2017)
• Mutations in ANXA11 cause familial and sporadic amyotrophic lateral sclerosis, BN Smith et al. (2017)
• Clusterin expression is upregulated following acute head injury and localizes to astrocytes in old head injury, C Troakes et al. (2017)
• Aluminium in brain tissue in familial Alzheimer's disease, A Mirza et al. (2017)
• A dysfunctional blood-brain barrier and cerebral small vessel disease, AH Hainsworth et al. (2017)
• Translational models for vascular cognitive impairment: a review including larger species, AH Hainsworth et al. (2017)
• White matter tract signatures of impaired social cognition in frontotemporal lobar degeneration, L Downey et al 2015
• Functional neuroanatomy of auditory scene analysis in Alzheimer's disease, H Golden et al 2015
• Developmental regulation of tau splicing is disrupted in stem cell-derived neurons from frontotemporal dementia patients with the 10 + 16 splice-site mutation in MAPT, T Sposito et al 2015
• A 30-unit hexanucleotide repeat expansion in C9orf72 induces pathological lesions with dipeptide-repeat proteins and RNA foci, but not TDP-43 inclusions and clinical disease, P Gami et al 2015
• First effects of rising amyloid-β in transgenic mouse brain: synaptic transmission and gene expression, D Cummings et al 2015
• Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology, E Clayton et al 2015

• Mirzaei N, Tang SP, Ashworth S, Coello C, Plisson C, Passchier J, Selvaraj V, Tyacke RJ, Nutt DJ, Sastre Met al., 2016, In vivo imaging of microglial activation by positron emission tomography with [(11) C]PBR28 in the 5XFAD model of Alzheimer’s disease., Glia, Vol: 64, Pages: 993-1006
• Scott G, Ramlackhansingh AF, Edison P, Hellyer P, Cole J, Veronese M, Leech R, Greenwood RJ, Turkheimer FE, Gentleman SM, Heckemann RA, Matthews PM, Brooks DJ, Sharp DJet al., 2016, Amyloid pathology and axonal injury after brain trauma, NEUROLOGY, Vol: 86, Pages: 821-828, ISSN: 0028-3878.
• Parr C, Mirzaei N, Christian M, Sastre Met al., 2015, Activation of the Wnt/beta-catenin pathway represses the transcription of the beta-amyloid precursor protein cleaving enzyme (BACE1) via binding of T-cell factor-4 to BACE1 promoter, FASEB JOURNAL, Vol: 29, Pages: 623-635, ISSN: 0892-6638
• Fan Z, Aman Y, Ahmed I, Chetelat G, Landeau B, Chaudhuri KR, Brooks DJ, Edison Pcloseet al., 2015, Influence of microglial activation on neuronal function in Alzheimer’s and Parkinson’s disease dementia, ALZHEIMERS & DEMENTIA, Vol: 11, Pages: 608-621, ISSN: 1552-5260
• Can Studies of Neuroinflammation in a TSPO Genetic Subgroup (HAB or MAB) Be Applied to the Entire AD Cohort? Z Fanz et al 2015
• Systemic administration of fibroblast growth factor-2 (FGF2) reduces BACE1 expression and amyloid pathology in APP23 mice, L Katsouri et al 2015
• Modulation of inflammation in transgenic models of Alzheimer’s disease, A Birch et al 2015
• Phenotypic profile of alternative activation marker CD163 is different in Alzheimer’s and Parkinson’s disease, P Pey et al 2014
• VCP mutations are not a major cause of familial amyotrophic lateral sclerosis in the UK, C Kwok et al 2015
• Mapping CSF biomarker profiles onto NIA-AA guidelines for Alzheimer’s disease, P Alexopoulos et al 2015
• Dhanjal NS, Wise RJS, 2014, Frontoparietal Cognitive Control of Verbal Memory Recall in Alzheimer’s Disease, ANNALS OF NEUROLOGY, Vol: 76, Pages: 241-251, ISSN: 0364-5134.
• Lill CM, Rengmark A, Pihlstrom L, Fogh I, Shatunov A, Sleiman PM, Wang L-S, Liu T, Lassen CF, Meissner E, Alexopoulos P, Calvo A, Chio A, Dizdar N, Faltraco F, Forsgren L, Kirchheiner J, Kurz A, Larsen JP, Liebsch M, Linder J, Morrison KE, Nissbrandt H, Otto M, Pahnke J, Partch A, Restagno G, Rujescu D, Schnack C, Shaw CE, Shaw PJ, Tumani H, Tysnes O-B, Valladares O, Silani V, van den Berg LH, van Rheenen W, Veldink JH, Lindenberger U, Steinhagen-Thiessen E, Teipel S, Perneczky R, Hakonarson H, Hampel H, von Arnim CAF, Olsen JH, Van Deerlin VM, Al-Chalabi A, Toft M, Ritz B, Bertram Lclose, 2015, The role of TREM2 R47H as a risk factor for Alzheimer’s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson’s disease, ALZHEIMERS & DEMENTIA, Vol: 11, Pages: 1407-1416, ISSN: 1552-5260

If you have equipment and resources you’d like shared with the Network Centre, get in touch.

Equipment	Point of Contact	Grant Scheme
Nanodrop ND2000c Spectrophotometer	Tamas Revez	ARUK Equipment Grant
EyeLink II Head Mounted Eye Tracking System	Sebastian Crutch	ARUK Equipment Grant
Compact X4 automatic X-ray film processor from Xograph imaging systems	Tamas Revez	ARUK Equipment Grant
Leica Laser Capture Microdissection Microscope LMD7000	John Hardy	ARUK Equipment Grant