We fund world class researchers to unpick causes and understand the complexities of the diseases that cause dementia.
By increasing our understanding of that changes in the brain that cause dementia, research will get us to a cure.
To advance this mission, Alzheimer’s Research UK became a founding funder of the UK Dementia Research Institute (UK DRI). Made up of seven centres across the UK, dementia researchers work together like never before towards a shared vision of changing the outlook for people living with dementia.
To make this long-term investment possible, Alzheimer’s Research UK joined forces with the Medical Research Council and Alzheimer’s Society. First announced in 2015, the UK DRI is now home to over 700 researchers from a range of disciplines.
This landmark investment in dementia research supports the people and ideas inspiring our search to find life-changing treatments for dementia.
Current projects and initiatives
Understanding the spark that ignites Alzheimer’s disease
Prof Louise Serpell from the University of Sussex to investigate what triggers the first stages of protein misfolding in Alzheimer’s disease
Mapping a key protein in the brain in Alzheimer’s disease
Researchers from the University of Bristol are using innovative techniques to visualise the distribution of a key protein responsible for regulating blood pressure in the brain.
Infections and Alzheimer’s disease: the consequences for tau.
A PhD student at the University of Southampton will investigate how bacterial infections increase the spread of tau protein in the brain.
Using new DNA technology to reveal the role of genes in neurodegenerative diseases
Professor Henry Houlden and his team are looking at how the shape and the speed of tau formation is influenced by changes in the MAPT gene, which could potentially open up new avenues for treatment.
Using large data collections to understand the risk of developing Alzheimer’s disease.
Researchers at University of Exeter are analysing large data collections to understand how a key risk gene affects the brain and our chances of developing Alzheimer’s.
Finding a way to stop toxic tau protein from building up in Alzheimer’s disease.
A PhD student at the University of Exeter will look at ways to reduce tau tangles by targeting immune cells in the brain.
What makes a neuron vulnerable to early Alzheimer’s disease?
PhD student at Imperial College London will work to reveal why certain nerve cells are more susceptible to damage in Alzheimer’s disease.
Understanding how the brain’s immune cells play a role in familial British dementia.
UCL PhD student is investigating a rare genetic form of dementia.
Can zebrafish show us how amyloid causes sleep disruption?
Dr Guliz Ozcan at University College London will look to better understand how small amyloid proteins cause insomnia in people with Alzheimer’s disease.