How does genetics affect Alzheimer’s progression?

Researchers in Exeter are investigating how changes in the activity of genes can affect Alzheimer's progression

Researching

Causes

Prof Jonathan Mill is leading a major project researching the genetic mechanisms involved in the progression of Alzheimer’s disease. He will team up with pharmaceutical company Eli Lilly, who are providing matched funding for the project.

This project aims to shed more light on the mechanisms involved in Alzheimer’s disease and to help identify new treatments.

 

Prof Mill said:

“We’re delighted Alzheimer’s Research UK has funded our project, which aims to test the hypothesis that the development of Alzheimer’s disease is associated with changes in the activity of genes in affected brain regions. The project brings together experts in genomics, informatics and neuroscience, and represents a novel approach for identifying the mechanisms involved in the progression of this terrible disease.”

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Awarded to
Professor Jonathan Mill

Institution
University of Exeter Medical School

Current Award
£433,549.03

Dates
1 March 2019 - 28 February 2022

Full project name
Regulatory genomic variation in rodent models of amyloid and tau neuropathology