Can drugs that boost noradrenaline improve memory?
Researchers will work with people who have early Alzheimer’s disease see if two drugs that boost noradrenaline will improve memory and concentration.
Dementia is caused by physical diseases, most commonly Alzheimer’s disease.
Brain damage in Alzheimer’s first happens in the locus coeruleus.
This small brain structure is the main producer of a chemical called noradrenaline which plays a key role in thinking, memory and behaviour.
Early symptoms may be linked to damage to this structure.
This ambitious project will test if a drug that enhances noradrenaline will improve memory and concentration in early Alzheimer’s.
This research will open exciting new avenues of exploration for detection of the earliest changes in the disease and ways to improve symptoms.
This will help us make life-changing breakthroughs possible.
Dr Dorothea Hammerer
University College London
1 September 2019 - 31 August 2023
Full project name:
Noradrenergic treatment for the symptoms of Alzheimer's disease