Can drugs that boost noradrenaline improve memory?

Dementia is caused by physical diseases, most commonly Alzheimer’s disease.

Brain damage in Alzheimer’s first happens in the locus coeruleus.

This small brain structure is the main producer of a chemical called noradrenaline which plays a key role in thinking, memory and behaviour.

Early symptoms may be linked to damage to this structure.

This ambitious project will test if a drug that enhances noradrenaline will improve memory and concentration in early Alzheimer’s.

This research will open exciting new avenues of exploration for detection of the earliest changes in the disease and ways to improve symptoms.

This will help us make life-changing breakthroughs possible.