Can drugs that boost noradrenaline improve memory?

Researchers will work with people who have early Alzheimer’s disease see if two drugs that boost noradrenaline will improve memory and concentration.

Researching

Treatments

Dementia is caused by physical diseases, most commonly Alzheimer’s disease. Brain damage in Alzheimer’s first happens in the locus coeruleus. This small brain structure is the main producer of a chemical called noradrenaline which plays a key role in thinking, memory and behaviour.  Early symptoms may be linked to damage to this structure.

This ambitious project will test if a drug that enhances noradrenaline will improve memory and concentration in early Alzheimer’s. This research will open exciting new avenues of exploration for detection of the earliest changes in the disease and ways to improve symptoms. This will help us make life-changing breakthroughs possible.

Help us fund more projects like this one

Dementia is one of the world’s greatest challenges. It steals lives and leaves millions heartbroken. But we can change the future.

Your donation will help power research

Awarded to
Dr Dorothea Hammerer

Institution
University College London

Current Award
£419,428.59

Dates
1 September 2019 - 31 August 2023

Full project name
Noradrenergic treatment for the symptoms of Alzheimer's disease