Drop in blood pressure linked with dementia risk

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By Alice Tuohy | Wednesday 25 July 2018

Neurology: Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline

A team of US scientists have identified an increased dementia risk for people who in midlife experience orthostatic hypotension – unusually high drops in blood pressure when standing up suddenly. The findings were published in the scientific publication, Neurology.

Dr Laura Phipps, from Alzheimer’s Research said:

“This research adds to a growing and complex picture of how blood pressure changes throughout life can impact the brain. While many studies have focused on the risks of high blood pressure, these findings suggest that transient low blood pressure could also have a long-term impact on the brain. We now need to see a concerted research effort examining the potential mechanisms underpinning changes in blood pressure and an increased dementia risk, to help develop preventions and  treatments that could slow the onset or progression of the condition.”

“There is now mounting evidence to suggest that what’s good for the heart is also good for the brain. As well as maintaining a healthy blood pressure, the best current evidence suggests that not smoking, only drinking alcohol in moderation, staying mentally and physically active, eating a balanced diet, and keeping cholesterol levels in check can all help to keep our brains healthy as we age.”


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Alice Tuohy