Your support is funding pioneering dementia research that will bring us closer to a cure. With your help, we will keep going until every person is free from the fear, harm and heartbreak of dementia.
Join us today and fundraise for a cure.
THE FIRST TREATMENTS THAT CAN SLOW ALZHEIMER’S DISESASE ARE NOW ON THE HORIZON. THIS IS JUST THE BEGINNING.
What your fundraising has achieved so far
We have invested over £176 million into over 1,100 research projects since 1998 helping us to get closer to a cure. This is only possible because of the generosity of people like you, and the research you fund.
Our researchers are making incredible progress.
They’ve worked with scientists across 72 countries, making more than 4,500 discoveries that are bringing us closer to a cure.
Here are just some of the amazing advances from our scientists:
Creating revolutionary ways to study diseases that cause dementia in the lab. These are used by scientists across the globe, revealing new clues into how to treat, diagnose and prevent dementia in the future.
Building our understanding of brain health, helping us prevent more cases of dementia before they even start.
Uncovering over 75 risk genes, providing vital clues for drug discovery. Our scientists’ discovery of the TREM2 risk gene has led to experimental Alzheimer’s drugs in clinical trials today.
Developing experimental dementia drugs, with our Drug Discovery Alliance working on over 20 potential new treatments for dementia right now.
Helping build the evidence so researchers can develop blood tests for diagnosing Alzheimer’s disease. This will help people get a faster and more accurate diagnosis opening the door for a cure.
For every £1 donated in 2022...
73p powered our life-changing research and helped people to understand and take action on dementia.
27p helped to raise the next £1 and fund essential running costs.
WE’RE FUNDING MORE THAN 200 RESEARCH PROJECTS, INCLUDING A PROJECT THAT USES NEW DNA TECHNOLOGY TO INVESTIGATE ALZHEIMER’S GENES.
Professor Henry Houlden and his team are studying the build-up of a protein in the brain, called tau. Tau build-up cause nerve cells to die, damaging the brain and causing diseases like Alzheimer’s disease and frontotemporal dementia (FTD) to develop.
The team want to know if certain genetic changes in a gene called MAPT can affect the way tau builds up and will use cutting-edge DNA technology to study this.
Their findings could lead to ways to prevent tau tangles from developing, opening up new treatment avenues for Alzheimer’s disease and FTD.
Want to find out more?
NEW TREATMENTS
We are now entering a new era, with two new treatments for Alzheimer’s disease on the horizon. Lecanemab and donanemab work by removing the build-up of a protein called amyloid from the brain.
Although they only work for people with early-stage disease, and come with some significant side effects, they are the first drugs that slow the progression of the disease rather than just treating its symptoms.
And with 141 potential drugs for Alzheimer’s disease being tested in 187 trials across the globe, we are finally gaining ground on tackling this devastating condition.
But we need to keep going so we find newer and better treatments for all forms of dementia.
And with researchers at our Drug Discovery Alliance working on more than 20 drug discovery projects right now, we are determined to find a cure.
Please support us in our search for a cure.
Drugs like lecanemab and donaemab show us what can be achieved through the power of research.
But we need to find drugs that go beyond removing amyloid, and to find treatments for other forms of dementia, such as dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD).
And we’re working on new ways to diagnose the disease, so that more people receive a swift, accurate and early diagnosis and can access treatments and research.
Our research is also looking at ways to prevent dementia from happening in the first place, and revealing new clues to how we can all reduce our risk of developing it.
It’s only through your support for our life-changing research that will end the fear, harm and heartbreak of dementia.
Please support us to help find a cure.
Your support means so much to everyone living with dementia in the UK, and the 34 million people who know someone affected by it. You can read some of these personal stories on our blog.
With your support we can find a cure for every single person affected by dementia. Research can make the heartbreak of dementia a thing of the past. Read more about the exciting projects we’re funding on our research project page.
"Your support means so much to everyone living with dementia in the UK, and the 34 million people who know someone affected by it."
- Hilary Evans-Newton, Chief Executive, Alzheimer's Research UK
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