£50,000 to £350,000
31 January 2024
The Major project grant scheme provides funds for intermediate to large scale research projects. Research question should be framed to understand/diagnose/treat/ reduce risk of Alzheimer’s disease and other dementias.
Duration: Up to five years.
Provided to cover salaries (research, technical, students etc), equipment, animal costs and running costs (consumables, travel etc).
1 November 2023
31 January 2024
The lead applicant and point of contact must be based in a UK academic/research institution. However, the application can include researchers or institutions outside the UK.
The Lead Applicant is expected to have a contract (fixed term or tenure) which covers the proposed duration of the grant. Alzheimer's Research UK can contribute to salaries of co-applicants that do not have tenure or fixed term contracts but not to Lead Applicant salaries.
If the Lead Applicant does not hold a tenure appointment, the application must include a co-applicant that does.
If the project requires ethical approval and/or Home Office licences, the award is dependent upon the requisite approvals being granted.
If you are applying for funds for translational research, such as drug discovery and development work, please consider a partnership with the Drug Discovery Alliance.
See our Eligibility Guidelines for further information.
Applications are made via our grant application website.
Grant schemes only appear on this website when the round is open and we are accepting new applications.
Alzheimer’s Research UK is a member of the Association of Medical Research Charities and follows their guidelines for best practice in peer review. Grants are awarded entirely on scientific merit in relation to ARUK’s remit and on the basis of open competition. The quality of the application and applicants is the key determinant of outcome, although the strength of the dementia research environment within the institution is also considered.
Our Grant Review Board (GRB) members are asked to read a subset of applications related to their area of expertise and provide a score based on whether an application should proceed to the next stage of review.
Applications requesting funding of over £50,000 per year are subjected to external peer review. Applications are sent to researchers in the UK and worldwide who specialise in the area of the application, but who do not have a conflict of interest and are not a member of the GRB. The comments made by the external reviewers are made available to the GRB members.
The applicants are provided with anonymised copies of the external reviews and given the opportunity to provide a written response.
Applications for research studies that involve people require lay review. Applicants are requested to complete a lay summary of their application which is sent to lay review volunteers for comments. The comments made by lay reviewers are fed back to the applicant for rebuttal and are also made available to the GRB members.
Discussion in meeting
Each application is allocated to two GRB members, based roughly on their areas of expertise. The two members will present the application to the rest of the board, including any relevant information from external reviews or applicant responses. A short discussion will follow before the GRB score the application. Applications for each grant scheme are ranked by their average score and recommendations for funding are made.
Those applications recommended for funding by the GRB are presented to the trustees for final approval.
In the last three years Alzheimer’s Research UK has received 127 applications for Major Project grants. 25 of these projects were awarded funding.
The terms and conditions of grant differ for each grant scheme and contracts are drawn up individually once the grants have been awarded.
All grant holders are expected to report on the progress of their project on a regular basis. Read more about our reporting requirements on the measuring impact page.
For more information about any of the grant schemes or the application process please contact the Research Team firstname.lastname@example.org or 0300 111 5555