Early-onset Alzheimer’s disease
Using data from brain donations to investigate the impact of multiple underlying causes of dementia
Use information from the Brains for Dementia Research Programme to find out which disease combinations lead to a more rapid decline of memory and thinking skills.
Detecting amyloid in action
Dr Steven Quinn at the University of York will use a state-of-the-art microscope to look at the interactions between proteins involved in Alzheimer’s, which will paint a clearer picture of how the disease progresses
Using brain scans to investigate changes in the brain over time
Prof Nick Fox and Prof Jon Schott are studying brain scans to investigate changes in the brain over time in a longitudinal amyloid-PET/MRI study of the 1946 birth cohort.
Just below the surface of the brain
Researchers at University College London seek to identify changes just under the surface of the brain that could indicate the early stages of Alzheimer’s disease
Designing treatments that stop protein clumping
Researchers at the University of Groningen are working to design drugs to stop the clumping of toxic proteins in the diseases that cause dementia.
Using stem cells and specialised chambers to unravel dementia
Researchers at the University of Manchester are using sophisticated chambers to monitor how toxic proteins spread in dementia and the complex relationship between brain cells and their blood supply.
Treating hearing loss in people at a high risk of dementia
Researchers at the University College London are developing a pilot trial to ensure people with hearing loss and mild cognitive dementia start and continue to use hearing aids. They will follow-up to evaluate its effectiveness in reducing the risk of dementia.
Can we get higher risk adults to eat well and exercise?
Researchers at the University of East Anglia are exploring the effects of exercise and Mediterranean style diet on dementia risk
Building a tool to predict dementia risk
Researchers at the University of Manchester are developing a tool that could be used to identify people who would benefit from early preventative measures and develop personalised information to help individuals reduce their risk of dementia.
Can we reduce the risk of dementia in the over 75’s?
Researchers at the University of Cambridge are exploring an whether an internet based intervention could encourage healthy lifestyle changes in people aged over 75, who are at a higher risk of developing dementia.
