Alzheimer’s disease
Solving a 30-year mystery – how an important Alzheimer’s risk gene affects our brain
Lots of factors affect a person’s risk of getting Alzheimer’s disease, the number one cause of dementia. It’s a complex mix of lifestyle, health and age, but our genetic makeup plays a particularly important role in determining whether we will get Alzheimer’s.
Looking at the blood brain barrier to help identify new treatments for dementia
Researchers in Newcastle are developing a new technique to screen for new drug targets to treat Alzheimer’s disease
Finding ways to boost resilience to Alzheimer’s disease
Researchers from the University of Oxford will investigate how and why some people are ‘resilient’ to developing dementia to find new treatment targets.
Understanding the links between obesity in parents and children’s future dementia risk
Researchers are unpicking the links between obesity in parents and the effect to their children’s risk of developing Alzheimer’s later in life
Investigating how mutations affect brain inflammation in frontotemporal dementia
Researchers at King’s College London are unpicking how mutations in specific proteins affect brain inflammation in frontotemporal dementia.
Understanding the role of metal particles in Alzheimer’s and their potential for diagnosis and treatment
Researchers at Keele University will develop ways to ‘see’ iron in the brain and explore how metals could be used as treatment targets and indicators of Alzheimer’s disease.
Understanding the link between sport and dementia risk
This project will review the current evidence around the benefits and risks of sport and, through collaboration with stakeholders in research, clinicians, and sporting bodies, define future research priorities in this space.
What happens when the barrier between blood vessels and brain cells breakdowns in Alzheimer’s disease?
Researchers are investigating whether the changes in cell metabolism at the barrier between blood vessels and brain cells contributes to brain degeneration.
Understanding the link between wellbeing and brain function in dementia
Researchers will analyse data from large-scale studies and databases to understand the link between wellbeing and brain function decline in dementia.
Are risk factors for heart disease linked to brain health?
Researchers will analyse data from large studies to explore whether risk factors for heart disease in early life will impact brain health.
