Risk factors

posterior cortical atrophy

The symptoms of PCA are caused by changes in the brain cells that process visual information from our eyes.

What causes posterior cortical atrophy?

In PCA caused by Alzheimer’s disease, it is not clear why the disease affects this part of the brain more so than the areas affected by typical Alzheimer’s, which generally are involved in memory.

It is thought that what makes up a person’s risk of developing PCA is similar to other types of dementia. This is a complex mix of factors including our:

  • Elderly-Mandarin

    age

  • RS2269_Icons-ARUK-Fearless Orange_DNA

    genes

  • Heart health-Mandarin

    health

  • Running-Teal

    lifestyle

  • Pollution-Orange & Steel white

    and environment

Scientists are working hard to find out more, as well as exploring specific genetic or lifestyle risk factors for the condition.

Downloads

Dementia information

Find out more about the symptoms and causes of posterior cortical atrophy, and the treatments currently available.

Order health information

Alzheimer's Research UK has a wide range of information about dementia. Order booklets or download them from our online form.

Complete the survey

Was this information helpful?
Let us know what you think by filling out this short survey.

Information on this page does not replace any advice that doctors, pharmacists or nurses may give you.

This information was updated in April 2025 and is due to be reviewed in April 2027. It was written by Alzheimer’s Research UK’s Information Services team with input from lay and expert reviewers. Please get in touch if you’d like a version with references or in a different format.
This information is produced with support from The Perfume Shop who had no input into the content.

TPS LOGO Primary Logo