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CMAJ: Absolute 10-year risk of dementia by age, sex and APOE genotype: a population-based cohort study Scientists in Denmark have estimated the proportion of people with a common dementia risk gene who will develop dementia in each of the three decades following their 60th birthday. The findings are published in the medical publication, CMAJ. Dr […]
JAMA Ophthalmology: Association of Preclinical Alzheimer Disease With Optical Coherence Tomographic Angiography Findings A team of scientists at Washington University have found that a non-invasive eye test could help identify people with brain changes linked to early Alzheimer’s disease. The findings are published today (Thursday 23 August) in the scientific publication, JAMA Ophthalmology. Dr Sara Imarisio, […]
JAMA: Association of Cardiovascular Health Level in Older Age With Cognitive Decline and Incident Dementia A team of scientists in France has identified a decreased dementia risk for people who have better heart health. The findings are published today (Tuesday 21 August) in the scientific publication, JAMA. Dr Sara Imarisio, Head of Research of Alzheimer’s Research […]
People in Nordic countries, North America, Australia, and New Zealand have the best spatial navigational abilities, according to a new study led by UCL and the University of East Anglia. Researchers assessed data from over half a million people in 57 countries who played a specially-designed mobile game, which has been developed to aid understanding […]
The BMJ: Alcohol consumption and risk of dementia: 23-year follow-up of Whitehall II cohort study A new study has examined the links between alcohol consumption in midlife and later life dementia risk, finding that abstaining from drinking or drinking over 14 units a week was associated with a higher dementia risk than drinking 1-14 units […]
The pharmaceutical companies Eisai and Biogen have presented results of a phase 2 clinical trial of the potential Alzheimer’s disease drug, BAN2401. The presentation at the Alzheimer’s Association International Conference 2018 in Chicago, was the first look at data from the trial and follows an earlier announcement of positive results. BAN2401 successfully reduced levels of the […]
Neurology: Association of orthostatic hypotension with incident dementia, stroke, and cognitive decline A team of US scientists have identified an increased dementia risk for people who in midlife experience orthostatic hypotension – unusually high drops in blood pressure when standing up suddenly. The findings were published in the scientific publication, Neurology. Dr Laura Phipps, from […]
Nature Communications: Blood-brain barrier opening in Alzheimer’s disease using MR-guided focussed ultrasound Canadian scientists have shown that a treatment to open the blood brain barrier, which involves implanting an ultrasound treatment alongside an injection of a small gas bubble into the bloodstream is safe in a study of four people with dementia. The findings are […]
Research presented at the Alzheimer’s Association International Conference 2018 today (Wednesday 25 July) has found treating high blood pressure towards the ideal range may help reduce the risk of memory and thinking problems. Carol Routledge, Director of Research at Alzheimer’s Research UK, said: “We know that high blood pressure is a risk factor for dementia, […]
Four new studies being presented at the Alzheimer’s Association International Conference (AAIC) 2018 in Chicago today (Tuesday 24 July) have highlighted a link between the action of the gut and liver, and brain changes associated with Alzheimer’s disease. Fat production in the liver and the link to Alzheimer’s risk Bile acid levels associated with key […]