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Posted on 10 Nov

Sleep problem linked to changes in hallmark Alzheimer’s protein

Researchers in the US have found a link between the sleep disorder, obstructive sleep apnoea, and levels of a protein involved in Alzheimer’s disease. Their findings are published today in the American Journal of Respiratory and Critical Care Medicine. Obstructive sleep apnoea (OSA) involves periods of disordered breathing, which occur when a person’s upper airway […]

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Posted on 08 Nov

Memory brain areas particularly vulnerable to reduced blood flow

A new study from researchers in the US suggests that older people whose hearts pump less blood have reduced blood flow in areas of the brain that control memory. The study was published today in the online issue of Neurology, the medical journal of the American Academy of Neurology. To support its many functions, the […]

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Posted on 04 Nov

Blood-plasma infusions safe to be explored as Alzheimer’s treatment

Scientists in the US have found that regular infusions of blood plasma from young donors are safe to explore as a treatment option for people living with Alzheimer’s disease. The results from the PLASMA trial, short for Plasma for Alzheimer’s Symptom Amelioration, are presented at Clinical Trials Alzheimer’s Disease Conference in Boston, US today. Infusions […]

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Posted on 02 Nov

Positive results from Alzheimer’s drug in Phase 1 clinical trial extension

The pharmaceutical company Biogen has today announced the results of an extended phase 1b clinical trial of the potential Alzheimer’s disease drug, aducanumab. Results from the extended early stage trial, were announced today at Clinical Trials in Alzheimer’s Disease (CTAD) conference in Boston. Aducanumab is an antibody that targets amyloid, a protein that builds up […]

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Posted on 01 Nov

Inflammation in middle age linked to reduction in brain size

Scientists in the US have found a link between inflammation in middle age and a reduction in brain size in later life. The findings are published today in the journal of the American Academy of Neurology. Alzheimer’s disease involves a complex set of biological processes that cause physical damage to parts of the brain. Researchers […]

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Posted on 31 Oct

Study shows Alzheimer’s protein passing from blood to brain in mice

Scientists in China collaborating with the University of British Columbia, have found for the first time that amyloid present in a brain can trigger features of Alzheimer’s disease in a separate brain via a shared blood supply. The findings are published today in the journal, Molecular Psychiatry. Alzheimer’s disease is the most common cause of […]

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Posted on 30 Oct

Nutritional drink shows mixed results in early Alzheimer’s trial

Researchers investigating the effects of a commercially available nutritional drink, have found limited evidence of any benefit for people with very early memory and thinking problems. Trials of the drink, known as Souvenaid, failed to show any reduction in the rate of overall memory and thinking decline but did point to potential improvements in other […]

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Posted on 25 Oct

Dementia reduced with blood thinning drugs for atrial fibrillation

Swedish scientists studying the number of new dementia cases in people with atrial fibrillation (an abnormal heart rhythm) have found that treatment with oral anticoagulants (OACs) reduces the risk of subsequent dementia. The results are published today in the Journal of European Cardiology. Dr Carol Routledge, Director of Research at Alzheimer’s Research UK said: “Stroke […]

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Posted on 12 Oct

Menopause linked to changes in brain energy use

Researchers from Weill Cornell Medicine and the University of Arizona Health Sciences have found that women’s brains use less energy during the menopause. The reduction in energy use by the brain was found to be similar to that seen in people with Alzheimer’s disease in a previous small study. The results of the work were […]

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Posted on 10 Oct

TREM2 gene carries benefits as well as risks in Alzheimer’s disease

Researchers at the Washington University School of Medicine have studied the role of the Alzheimer’s risk gene TREM2, finding surprising evidence that the gene could also be protective against damage caused by tau tangles – a key hallmark of the disease. The results are published in the journal Proceedings of the National Academy of Sciences. […]

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