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Posted on 14 Feb

Genetic technique reverses Alzheimer’s processes in mice

Researchers in the US have used genetic techniques to slow the progression of Alzheimer’s in mice that show features of the disease. The study, which centered around a protein called BACE1, was reported today in the Journal of Experimental Medicine. In humans, BACE 1 is involved in the production of a hallmark Alzheimer’s protein called […]

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Posted on 13 Feb

Arthritis drugs linked to lower Alzheimer’s risk

Scientists from the University of Southampton have teamed up with researchers from the University of Oxford to look at whether existing drugs for arthritis have any effect on a person’s risk of developing dementia. By looking at two groups of people – one receiving the drug treatment and one not – they found that fewer […]

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Posted on 07 Feb

Positive beliefs on ageing associated with reduced dementia risk

Scientists in the US have researched how positive beliefs about ageing are linked with a reduced risk of dementia risk, including in people who carry one of the major risk genes, APOE4. The researchers found those with the APOE4 gene who held positive beliefs about ageing were less likely to develop dementia than who held […]

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Posted on 06 Feb

Intervention benefits people living with dementia in care homes

Researchers from the University of Exeter have explored the use of an interventional-type care approach in UK care homes, finding it improves the lives of people with dementia. The trial combines the training of care home staff, increasing the quality of interactions between nurses and people living with dementia and guidance on the use of […]

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Posted on 06 Feb

Brain stimulation improves word recall in severe epilepsy

Researchers have found that electrically stimulating regions of the brain can improve the ability of people’s memory. Their findings were reported in the scientific publication Nature Communications. Dr David Reynolds, Chief Scientific Officer at Alzheimer’s Research UK, said: “While dementia involves a range of complex symptoms, memory problems are among the most common and can […]

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Posted on 05 Feb

Faults in the blood-brain barrier implicated in dementia

California based researchers have found that damage to cells known as pericytes, which surround small blood vessels in the brain, may trigger a chain of events that results in brain degeneration. The findings are published today in the scientific publication Nature Medicine. Dr Carol Routledge, Director of Research at Alzheimer’s Research UK, said: “It is […]

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Posted on 31 Jan

Pioneering research is using the eye to help detect Alzheimer’s disease

Today Alzheimer’s Research UK has announced a unique new funding partnership for two novel research projects exploring how the eye can be used as a window into the brain. In partnership with the charitable organisation Fight for Sight, Alzheimer’s Research UK has co-committed £30,000 worth of funding for two, one-year long research projects. Both pioneering […]

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Posted on 31 Jan

Blood based marker for Alzheimer’s disease shows diagnostic potential

Researchers in Japan and Australia have used the ratio of different forms of the hallmark Alzheimer’s protein, amyloid, in blood to detect those who have high levels of the protein in their brain. Their findings are published today in the scientific publication Nature and take researchers a step closer to developing a blood test for […]

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Posted on 30 Jan

Traumatic brain injury associated with dementia in large study

Swedish researchers have found a link between traumatic brain injury and an increased risk of dementia, in some cases 30 years after individuals experienced the injury. The findings are published today in the scientific publication PLOS Medicine. Dr Sara Imarisio, Head of Research at Alzheimer’s Research UK, said: “The association between head injuries and dementia […]

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Posted on 30 Jan

Brain stimulation shows promise for Alzheimer’s disease in early trial

Scientists in the US have found that electrically stimulating regions of the brain in three people with Alzheimer’s disease was safe and appeared to show an effect on thinking skills and day-to-day tasks in two of the volunteers. The findings are published today in the scientific journal, Journal of Alzheimer’s Disease. There has been no […]

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