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Posted on 14 Dec

UK DRI invests £1.5 million into Huntington’s disease

A progressive new research programme has just been funded by UK Dementia Research Institute (UK DRI), in its first investment in Huntington’s disease since the Institute was established last year. The programme will be led by Professors Gillian Bates & Sarah J Tabrizi from University College London (UCL) and will look to better understand the […]

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Posted on 11 Dec

High urea levels linked with Huntington’s disease

Scientists from New Zealand and the University of Manchester discovered a potential link between increased levels of brain urea and Huntington’s disease. Working primarily in sheep and then comparing data with human brain samples, they found increased levels of urea in brains of Huntington’s cases. Their findings are published today Monday 11 December in the […]

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Posted on 07 Dec

Hearing loss linked with increased dementia risk

Scientists led by researchers from Trinity College Dublin studied the link between age-related hearing loss and a decline in memory and thinking skills. Their work found that there was a small but significant link between loss of hearing, memory loss and risk of dementia. Their findings were published in the journal of JAMA Otolaryngology – […]

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Posted on 01 Dec

High BMI linked to increased risk of dementia later in life

Alzheimer’s & Dementia: Body mass index and risk of dementia: Analysis of individual-level data from 1.3 million individuals A new study led by researchers at University College London shows that people with a higher body mass index (BMI) in midlife are more likely to develop dementia. The findings, based on data from 39 studies of […]

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Posted on 30 Nov

Second phase III study results for anti-tau Alzheimer’s treatment released

Results of a second phase III clinical trial of Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTX) developed by TauRx Therapeutics as the first anti-tau treatment for people with mild Alzheimer’s disease have been announced. Results of the trial were published this week in the Journal of Alzheimer’s Disease. LMTX is a second-generation drug aimed at blocking the build-up of […]

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Posted on 28 Nov

Marriage is linked to reduced dementia risk

Researchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The research, which is a review of 15 existing studies, is being published today in the scientific publication, the Journal of Neurology Neurosurgery & Psychiatry. Dr Laura Phipps of […]

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Posted on 21 Nov

Dementia study sheds light on how damage spreads through brain

Scientists have revealed insights into how a key protein disrupts brain cells in dementia with Lewy bodies (DLB). Researchers say the findings shed light on the causes of DLB and will help to accelerate the search for a treatment. Results from the study are published in the scientific journal Brain. DLB is the third most […]

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Posted on 16 Nov

Frailty associated with greater dementia risk

Researchers at the University College of London (UCL) have studied the effect of frailty on the risk of developing dementia. The study found an association between an increase in frailty and an increased likelihood of developing dementia. Their findings are reported in the scientific publication, Scientific Reports. Researchers took a total of 8,722 older adults […]

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Posted on 16 Nov

Brain training activity linked with reduced risk of dementia

Researchers in the US have published results from a 10-year study into the effects of brain training activities on healthy older people. The study found a possible link between one type of brain training exercise a lower risk of dementia after 10 years. Their findings were published in the Journal of Alzheimer’s & Dementia: Translational […]

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Posted on 10 Nov

Understanding removal of brain fluid provides avenue for Alzheimer’s treatment

Researchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm shift in how scientists think about this process and could have future implications for tackling Alzheimer’s disease. The findings are published today in the scientific journal Nature Communications. […]

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