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Posted on 21 Mar

Phase III aducanumab trials for Alzheimer’s disease stopped early

Pharmaceutical companies Biogen and Eisai today (Thursday 21 March) announced they are to discontinue two phase III trials of the Alzheimer’s drug aducanumab. The ENGAGE and EMERGE trials were designed to evaluate the efficacy and safety of aducanumab in people with a confirmed diagnosis of mild cognitive impairment (MCI) or mild Alzheimer’s disease. Aducanumab is […]

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Posted on 20 Mar

New findings reveal insight about protein driving dementia after head injury

Nature letters: Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules Researchers at the MRC Laboratory of Molecular Biology at the University of Cambridge have found a key molecular difference between Alzheimer’s disease and a form of dementia brought on by head injury. The findings are reported today (Wednesday 20 March) in the […]

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Posted on 20 Mar

International research shows dementia rates falling by 15% per decade over last 30 years

International experts have today (Wednesday 20 March) presented research indicating that dementia incidence rates may be falling by up to 15% decade on decade. The findings will be discussed today (Wednesday 20 March) at the Alzheimer’s Research UK Conference 2019 in Harrogate. Dementia currently affects 850,000 people in the UK and the condition is now […]

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Posted on 19 Mar

Southampton student speaks at UK’s leading dementia conference

A PhD student from the University of Southampton will present research findings to 500 top dementia researchers at the Alzheimer’s Research UK Conference 2019 today (Tuesday 19 March). The annual event is the largest meeting of dementia researchers in the country. Jacqui Nimmo, 24, is the youngest speaker to be taking to the stage during […]

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Posted on 19 Mar

Harrogate hosts global experts at leading dementia conference

Nearly 500 scientists are arriving in Harrogate this week to share their latest research findings at the UK’s largest annual gathering of dementia researchers. The Alzheimer’s Research UK Conference 2019 is being held at the Harrogate Convention Centre on 19-20 March, with a jam-packed programme of talks and presentations over two days. Ahead of the […]

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Posted on 11 Mar

Eye changes could help detect Alzheimer’s

Ophthalmology Retina: Retinal microvascular and neurodegenerative changes in Alzheimer’s disease and mild cognitive impairment compared to controls New research in the US suggests that changes in the eye could help indicate if someone has Alzheimer’s disease. The findings are published today (Monday 11 March) in the journal, Ophthalmology Retina. The researchers investigated whether changes to […]

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Posted on 06 Mar

Hormone therapy linked to small Alzheimer’s risk increase

BMJ: Use of postmenopausal hormone therapy and risk of Alzheimer’s disease in Finland: nationwide case-control study Researchers in Finland have found that women who receive hormone replacement therapy are at slightly higher risk of developing Alzheimer’s. The findings are published today (Wednesday 6 March) in the scientific journal, BMJ. Hormone replacement therapy (HRT) is commonly […]

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Posted on 28 Feb

Watching TV for longer worsens memory

Nature Scientific Reports: Television viewing and cognitive decline in older age: findings from the English Longitudinal Study of Ageing Researchers at University College London have found that watching television for over three and a half hours a day is linked to a decline in performance on word learning and recall tasks. The findings are published […]

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Posted on 27 Feb

Blood pressure drugs show no effect on memory and thinking in trial

Neurology: Effects of blood pressure and lipid lowering on cognition: Results from the HOPE-3 study An international team of researchers has reported that a clinical trial of blood pressure and cholesterol-lowering medication in older people has shown no effect on memory and thinking over a six-year period. The results are published today (Wednesday 27 February) […]

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Posted on 20 Feb

Staying fit and mentally active linked with reduced dementia risk

Neurology: Cognitive and physical activity and dementia: A 44-year longitudinal population study of women Researchers in Sweden have found that women who exercise and stay cognitively active during midlife have a reduced risk of dementia in older age. The findings are published today (Wednesday 20 February) in the scientific journal, Neurology. In 1968, Swedish researchers […]

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