Genes and dementia
TREM2, discovered by Dr Rita Guerreiro in 2012, is a gene that codes for a protein produced by microglia – the brain’s immune defence cells.
Alzheimer’s Research UK recently awarded a £96,000 grant to Prof Kevin Morgan at the University of Nottingham to maintain and expand his large collection of DNA samples. This is to ensure he can continue his important research into the genetics of Alzheimer’s disease.
Scientists at Cardiff University studying the genetics of Alzheimer’s, have discovered 11 new areas of the genome linked to a higher risk of Alzheimer’s.
It often comes as a surprise to people that there’s a link between Down’s syndrome and dementia. But more than 60% of people with Down’s syndrome will develop Alzheimer’s – the most common form of dementia – before the age of 60. With our help, scientists are unravelling why.