Alzheimer’s is a disease that causes dementia. It is the most common cause of dementia, accounting for about two-thirds of cases in older people.
In Alzheimer’s, there are changes in the brain beyond those associated with normal ageing.
Among the most prominent are the build-up of two proteins, called amyloid and tau. Research suggests that both of these are involved in the disease process, and is revealing more about the sequence of events. As the disease progresses, more and more nerve cells in the brain become damaged. This damage leads to the symptoms of Alzheimer’s.
With our help, researchers are learning more about why these proteins build up in the brain and how they damage nerve cells. Research is underway to understand more about what happens in the brain during Alzheimer’s.
This information was updated in May 2016 and is due for review in May 2018. Please contact us if you would like a version with references.